58,011 research outputs found

    Systems thinking: critical thinking skills for the 1990s and beyond

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    This pdf article discusses the need for teaching systems thinking and critical thinking skills. Systems thinking and systems dynamics are important for developing effective strategies to close the gap between the interdependent nature of our problems and our ability to understand them. This article calls for a clearer view of the nature of systems thinking and the education system into which it must be transferred. Educational levels: Graduate or professional

    Helical motion of magnetic flux tubes in the solar atmosphere

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    Photospheric granulation may excite transverse kink pulses in anchored vertical magnetic flux tubes. The pulses propagate upwards along the tubes with the kink speed, while oscillating wakes are formed behind the wave front in a stratified atmosphere. The wakes oscillate at the kink cut-off frequency of stratified medium and gradually decay in time. When two or more consecutive kink pulses with different polarizations propagate in the same thin tube, then the wakes corresponding to different pulses may superimpose. The superposition sets up helical motions of magnetic flux tubes in the photosphere/chromosphere as seen by recent Hinode movies. The energy carried by the pulses is enough to heat the solar chrmosphere/corona and accelerate the solar wind.Comment: Accepted in ApJ

    Process facilitates photoresist mask alignment on SiC crystals

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    Growth of silicon dioxide on a silicon carbide crystal ensures proper orientation of photoresist masks on the crystals used for semiconductor devices. The crystal is heated in a water vapor-saturated gas to delineate p-n junctions that intersect the crystal surface

    Thin film process forms effective electrical contacts on semiconductor crystals

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    Process makes microscopic, low-resistance electrical contacts on hexagonal n-type silicon carbide crystals used for microelectronic devices. A vacuum deposition of aluminum is etched to expose the bare silicon carbide where the electrical contacts are made. Sputtering alternating layers of tantalum and gold forms the alloy film

    Sick of work or too sick to work? Evidence on health shocks and early retirement from the BHPS

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    We follow individuals as they retire using discrete-time hazard models applied to a stock sample from 12 waves of the British Household Panel Survey. Results confirm that health shocks are a determinant of retirement age and are quantitatively more important than pension entitlement. This is the case for both men and women and is observed for both a measure of health limitations and a measure of latent health status obtained from a generalized ordered probit model. Further, our results provide evidence that, for women, the health status of their partner impacts on their retirement decisions; an effect that is not evident for men

    Experimental results of the control of a vortical flow by tangential blowing

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    The results of a wind tunnel test to investigate the controlling effects of tangential, leading edge blowing on the vortical flow over a delta wing are given. Blowing is used to directly control the crossflow separation points at the rounded leading edge and hence, the trajectory of the feeding sheet and the location of the vortex. Experiments were conducted for both co-flowing and counter-flowing configurations over a range of angles of attack from 0 to 90 degrees. Results in the form of pressure distributions, overall force coefficients and flow mappings were obtained. The emphasis is on data presentation rather than detailed analysis. The initial results indicate that the co-flowing configuration was capable of extending the regime of stable, controlled vortical flow over the upper surface by approximately 30 degrees angle of attack for modest blowing requirements. Increases in maximum normal force coefficient of approximately 30% were achieved and significant rolling moments produced at angles of attack from 30 to 60 degrees. The counter-flowing configuration indicated only minor lift augmentation with the exception of an isolated occurrence at 20 degrees angle of attack. At that condition, with very weak blowing, a lift augmentation of approximately 20 was measured

    Force on a moving point impurity due to quantum fluctuations in a Bose-Einstein condensate

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    An analytic expression is derived for a force on a weak point impurity arising from the scattering of quantum fluctuations in a slow-moving, weakly interacting, three-dimensional Bose-Einstein condensate at zero temperature. In an infinitely extended geometry, this force is shown to exist at any arbitrarily small flow velocity below Landau's critical velocity. Furthermore, this force is shown to be directly proportional to the flow speed.Comment: v2: corrected notation and other minor change

    Epitope mapping using mRNA display and a unidirectional nested deletion library

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    In vitro selection targeting an anti-polyhistidine monoclonal antibody was performed using mRNA display with a random, unconstrained 27-mer peptide library. After six rounds of selection, epitope-like peptides were identified that contain two to five consecutive, internal histidines and are biased for arginine residues, without any other identifiable consensus. The epitope was further refined by constructing a high-complexity, unidirectional fragment library from the final selection pool. Selection by mRNA display minimized the dominant peptide from the original selection to a 15-residue functional sequence (peptide Cmin: RHDAGDHHHHHGVRQ; K-D = 38 nM). Other peptides recovered from the fragment library selection revealed a separate consensus motif (ARRXA) C-terminal to the histidine track. Kinetics measurements made by surface plasmon resonance, using purified Fab (antigen-binding fragment) to prevent avidity effects, demonstrate that the selected peptides bind with 10- to 75-fold higher affinities than a hexahistidine peptide. The highest affinity peptides (K-D approximate to 10 nM) encode both a short histidine track and the ARRXA motif, suggesting that the motif and other flanking residues make important contacts adjacent to the core polyhistidine-binding site and can contribute > 2.5 kcal/mol of binding free energy. The fragment library construction methodology described here is applicable to the development of high-complexity protein or cDNA expression libraries for the identification of protein-protein interaction domains
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